MOLECULAR DIAGNOSTIC

Molecular diagnostics is a collection of techniques used to analyze biological markers in the genome and proteome, and how their cells express their genes as proteins, applying molecular biology to medical testing.
CRISPR-based nucleic acid target detection is one of revolutionary method for Molecular Diagnostic. the Cas9, Cas12, Cas13 and Cas14 proteins have been used to successfully develop new rapid and sensitive tests for the diagnosis of infectious diseases, such as Zika virus, and non-communicable diseases involving nucleic acids, such as cancer. SignalChem DiagTech provides a panel of enzymes that can be used for development of CRISPR-based molecular diagnostic tests.

Name	Catalog Number	Species	Tag	Expression System	Genbank Number
Bsu DNA聚合酶大片段	BD01-E311U	Bacillus subtilis	Tag-free		AF008220
PsmCas13b核酸酶	CS13B-E312H		HIS		WP_028912271
Sau DNA 聚合酶大片段	SD01-E311U	Staphylococcus aureus	Tag-free		CP076105
T4 gp32蛋白	T4G32-C501H	Escherichia virus T4	HIS		J02513
T4 UvsX DNA 重组酶	T4SX-E311U	Escherichia virus T4	Tag-free		P04529
T4 UvsY 蛋白	T4SY-C501H	Escherichia virus T4	HIS		X04856
单链DNA结合蛋白	SS01-C501H	E.Coli	HIS		J01704
活性AsCas12a核酸酶	CS12A-E311H	Acidaminococcus	HIS		WP_021736722
活性ATP依赖 DNA解旋酶	AH01-E311H	E.Coli	HIS		WP_032255548
活性Cas12 (LbCpf1)核酸酶	C12CR-E241G	Lachnospiraceae	GST		ATB19154
活性Cas12 (LbCpf1)核酸酶	C12CR-E241H	Lachnospiraceae	HIS		ATB19154
活性Cas13a (LwC2c2)核酸酶	CS13A-E321H	Leptotrichia wadei	HIS		WP_021746774
活性LbuCas13a核酸酶	CS13A-E322U	Leptotrichia buccalis	Tag-free		WP_015770004
活性SpCas9核酸酶	CS09-E311H	Streptococcus pyogenes	HIS		AAK33936
活性TtCsm6 RNA内切酶	CS06-E311H	Thermus thermophilius	HIS		WP_011229148